NIOD CAIS3 Reviews

Unboxing NIOD CAIS 3 1:1 – Unboxing Copper Amino Isolate Serum

See the product, the colour, and the viscosity before buying it.

A Quick Look At NIOD CAIS3 1:1

  • Targets: Signs of Ageing.
  • Suitable for all skin types.
  • This can be used morning and evening.
  • Apply directly after cleansing and before any oils or creams.
  • Apply NIOD MMHC2 after CAIS3.
  • Check NIOD CAIS3 Conflicts here
  • CAIS3 is available in 2 sizes, 15ml & 30ml
  • Check the price in your currency here.

NIOD CAIS3 replaces Copper Amino Isolate Serum 2:1 and offers the same pro-collagen and pro-repair benefits without mixing.

NIOD CAIS 3 Reviews – Reviews of NIOD Copper Amino Isolate Serum

NIOD CAIS 3

About NIOD CAIS3

How To Use NIOD CAIS 3

  • Apply to the face morning and evening.
  • If you only wish to use it once a day, that´s fine.
  • Apply as the first step after cleansing.
  • Use before NIOD MMHC2 (hyaluronic) if using.

NIOD CAIS 3 1:1 Conflicts

Avoid using the following products in the same routine as NIOD CAIS. You can alternate them morning/evening or on different days.

NIOD CAIS3 PAO. The period after opening is 6 months.

Colour: Blue

Solution/Texture: Low viscosity. This is very, very thin. Absorbs really quickly.

About NIOD CAIS3

CAIS 3 1:1  is the third generation of NIOD’s multi-award-winning Copper Amino Isolate Serum. Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1.

As a highly focused effort to maintain healthy-looking skin, this pro-repair, pro-collagen serum offers a novel approach to indirectly target all visible signs of skin ageing. This indirect approach departs from the traditional thinking of addressing visible aspects of skin ageing individually and instead forms a foundation to respect skin health.

There is lots more information about NIOD CAIS3 on the NIOD website.

FAQs about NIOD CAIS3

These questions have been answered by Deciem on Social Media.

Is CAIS3 more potent than CAIS 2:1? Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1 and offers the same pro-collagen and pro-repair benefits without mixing.

Can I mix NIOD CAIS3 with my Buffet Serum, or it’s better to use it alone? You may apply The Ordinary “Buffet” after use. 

How is CAIS3 different to CAIS2? CAIS 3 1:1 is the third generation of NIOD’s multi-award-winning Copper Amino Isolate Serum. Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1. The previous generation of CAIS contained 2%% of pure GHK peptide, of which 1%% branched with copper ions upon mixing, forming 1%% freshly-assembled, pro-repair GHK-Cu (copper peptides) and leaving 1%% free-form, pro-collagen GHK peptide, for a final ratio of 1:1. The new formula omits mixing, instead of containing 1%% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1%% GHK peptide. Since this formula no longer requires additional GHK peptide for copper complexation, and no other copper source is added, it carries the name CAIS 3 1:1 as a reflection of the ratio of these ingredients in the formulation.

Can I use CAIS3 before SubQ Skin? Yes, you may.

MORE FAQS

Can CAIS 3 be used with SDSM? Yes, it can.

Would CAIS3 be used morning or night with Retinol (night) or vitamin C (morning)? It can be used twice daily if desired. If you wish to incorporate multiple Vitamin C’s, Retinoids, and/or Direct Acids into your skin care regimen, we suggest using them on alternate evenings and waiting until your skin has adjusted to one before introducing another.


Is CAIS3 the same texture as before, or is this formulation thicker? The same texture – ultra-lightweight. 

Can CAIS3 be used with NIOD ELAN? We would recommend using these in alternate routines.

Is it ok to use CAIS3 with my Retinol? We recommend using CAIS 3 1:1 in the AM and your Retinol in the PM.

Can we use NIOD CAIS3 or 2 in the same routine as Survival0? Yes, you can. You may apply CAIS2 or CAIS3 first.

Can you use CAIS3 with antioxidants like EUK or Pycnogenol, etc? We would recommend using Copper Peptides in alternate routines as strong antioxidants.

Is it ok to use CAIS with The Ordinary Glycolic Toner? We recommend using Copper Peptides in alternate routines as Direct Acids.

More FAQs

So is the mixing version of CAIS no longer going to be available? CAIS 3 1:1 will be replacing the previous formulation.

Is there any change regarding active ingredient concentrations? This formula no longer requires additional GHK peptide for copper complexation. However, the concentration of GHK-Cu is the same. 

Does this help blemish-prone skin? Just as a note – none of our products can be considered medical treatments for acne, so we suggest consulting with your physician to see what may work best for your skin.

Now that there is no more mixing involved with version 3, is the shelf life shorter than with CAIS 2? The shelf life is the same.

Looking forward to trying this out. Have you a similar product from the Ordinary. We hope you love it! You may wish to also explore The Ordinary “Buffet” + Copper Peptides 1%.

NIOD CAIS3 Reviews

Coming soon…

NIOD CAIS3 Ingredients

Aqua (Water), Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate, Tripeptide-1 Acetate, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.

Other Copper Products by Deciem

Where to buy NIOD

There are many places to buy NIOD. You can find a whole list of Deciem stores and online stockists here. Deciem offers free delivery on orders over 25€$. You can always find discounts on NIOD of sometimes up to 25%.