NIOD CAIS3 Reviews

NIOD CAIS3 Copper Amino Isolate Serum 3 1:1

Unboxing NIOD CAIS 3 1:1

See the product, the colour, and the viscosity before buying it.

NIOD CAIS3

NIOD CAIS3 replaces Copper Amino Isolate Serum 2:1 and offers the same pro-collagen and pro-repair benefits without mixing.

NIOD CAIS 3

A quick look at CAIS3 1:1

  • Targets: Signs of Ageing
  • Good for all skin types
  • Use AM & PM
  • Apply directly after cleansing and before any oils or creams
  • Check NIOD CAIS3 Conflicts here
  • CAIS3 is available in 2 sizes 15ml & 30ml
  • 30ml 90$US | 98$CAD | 65GBP | 76€ | 135$AUD
  • 15ml 60$US | $65$CAD | 41GBP | 49€ | 909$AUD
  • For all other currencies, please check the website.

About NIOD CAIS3

How To Use NIOD CAIS 3

  • Apply to face morning and evening.
  • Apply as the first step after cleansing.

NIOD CAIS 3 1:1 Conflicts

Avoid the following products in the same routine. You can alternate them morning/evening or on different days.

  • Acids
  • Pure Vitamin C
  • Retinol
  • Strong Antioxidants

NIOD CAIS3 PAO. The period after opening is 6 months

Colour: Blue

Solution/Texture: Very thin. Absorbs really quickly.

About NIOD CAIS3

CAIS 3 1:1  is the third generation of NIOD’s multi-award-winning Copper Amino Isolate Serum. Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1.

As a highly focused effort to maintain healthy-looking skin, this pro-repair, pro-collagen serum offers a novel approach to target all visible signs of skin ageing indirectly. This indirect approach departs from the traditional thinking of addressing visible aspects of skin ageing individually and instead forms a foundation to respect skin health.

More about NIOD CAIS3

The previous generation of CAIS contained 2% of pure GHK peptide, of which 1% branched with copper ions upon mixing, forming 1% freshly-assembled, pro-repair GHK-Cu (copper peptides) and leaving 1% free-form, pro-collagen GHK peptide, for a final ratio of 1:1.

The new formula omits mixing, instead of containing 1% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1% GHK peptide. Since this formula no longer requires additional GHK peptide for copper complexation, and no other copper source is added, it carries the name CAIS 3 1:1, as a reflection of the ratio of these ingredients in the formulation.

CAIS 3 1:1 also includes additional collagen-supporting peptides, Tripeptide-29, Acetyl Tetrapeptide-2 and Trifluoroacetyl Tripeptide-2. Its base combines mono-dispersed, plant-derived glycogen, availability-enhancing Myristoyl Nonapeptide-3 and cross-linked hyaluronic acid.

 PRO-HEALTH TECHNOLOGIES

1.0% Pure Undiluted Copper Tripeptide-1 (GHK-Cu) + 1.0% Pure Undiluted Tripeptide-1 (GHK)
CAIS 3 1:1 supplies 1% pure GHK peptide (Tripeptide-1), alongside 1% Copper Tripeptide-1 (GHK-Cu). Both GHK and GHK-Cu are found in nature and originally isolated from human plasma. The concentration of these peptides in human plasma continues to drop with aging past late teenage years.The natural role of these peptides as found in the human body includes activation of a wide range of skin health functions, including healing, immune function, collagen synthesis, fibroblast production and anti-inflammatory responses, while pure GHK offers strong pro-collagen support.

The 2% concentration of GHK and GHK-Cu in CAIS 3 1:1 aims to target visible signs of skin ageing, including textural irregularities, uneven tone, visibly enlarged pores and a general lack of healthy radiance normally present in younger skin. In short, the skin will look healthier with visible improvements with continued use.

PRO-COLLAGEN TECHNOLOGIES

9.0% Pure Undiluted Tripeptide-29
This amino acid sequence of Glycine-Proline-Hydroxyproline supports healthy collagen and works synergistically with GHK and GHK-Cu in this function.

4.0% Complex of Acetyl Tetrapeptide-2 and Trifluroacetyl Tripeptide-2
While pro-collagen peptides broadly focus on collagen quantity, these advanced peptide technologies support healthy collagen quality and assembly for skin that looks firmer and more evenly modeled.


INTEGRITY AND DELIVERY TECHNOLOGIES

0.10% Pure Mono-Dispersed Plant Glycogen
Glycogen is generally extracted from animal sources as a poly-dispersion. This advanced 100% plant-based mono-dispersed glycogen acts like hard spheres that protect the formulation peptides but break upon application for optimal dermal exposure.

9% Complex of Myristoyl Nonapeptide-3
This lipo-oligopeptide supports healthy skin renewal which is essential for maximizing skin availability of technologies in this formulation and those used in any subsequent treatments.

Hyaluronic Acid Crosspolymer
A unique cross-linked non-animal form of hyaluronic acid helps with the delivery of water and water-soluble actives through its nonequilibrium gel structure.

FAQs about NIOD CAIS3

These questions have been answered by Deciem on Social Media.

Is CAIS3 more potent than CAIS 2:1? Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1 and offers the same pro-collagen and pro-repair benefits without mixing.

Can I mix NIOD CAIS3 with my Buffet Serum or it’s better to use it alone? You may apply The Ordinary “Buffet” after use. 

How is CAIS3 different to CAIS2? CAIS 3 1:1 is the third generation of NIOD’s multi-award-winning Copper Amino Isolate Serum. Copper Amino Isolate Serum 3 1:1 replaces Copper Amino Isolate Serum 2:1. The previous generation of CAIS contained 2%% of pure GHK peptide, of which 1%% branched with copper ions upon mixing, forming 1%% freshly-assembled, pro-repair GHK-Cu (copper peptides) and leaving 1%% free-form, pro-collagen GHK peptide, for a final ratio of 1:1. The new formula omits mixing, instead of containing 1%% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1%% GHK peptide. Since this formula no longer requires additional GHK peptide for copper complexation, and no other copper source is added, it carries the name CAIS 3 1:1, as a reflection of the ratio of these ingredients in the formulation.

Can I use CAIS3 before SubQ Skin? Yes, you may.

MORE FAQS

Can CAIS 3 be used with SDSM? Yes, it can.

Would CAIS3 be used morning or night with Retinol (night) or vitamin C (morning)? It can be used twice daily if desired. If you wish to incorporate multiple Vitamin C’s, Retinoids, and/or Direct Acids into your skin care regimen, we suggest using them on alternate evenings and waiting until your skin has adjusted to one before introducing another.


Is CAIS3 the same texture as before or is this formulation thicker? The same texture – ultra-lightweight. 

Can CAIS3 be used with NIOD ELAN? We would recommend using in alternate routines.

Is it ok to use CAIS3 with my Retinol? We recommend using CAIS 3 1:1 in the AM and your Retinol in the PM.

Can we use NIOD CAIS3 or 2 in the same routine as Survival0? Yes, you can. You may apply CAIS2 or CAIS3 first.

Can you use CAIS3 with antioxidants like EUK or Pycnogenol, etc? We would recommend using Copper Peptides in alternate routines as strong antioxidants.

Is it ok to use CAIS with The Ordinary Glycolic Toner? We recommend using Copper Peptides in alternate routines as Direct Acids.

More FAQs

So is the mixing version of CAIS no longer going to be available? CAIS 3 1:1 will be replacing the previous formulation.

Is there any change regarding active ingredient concentrations? This formula no longer requires additional GHK peptide for copper complexation. However, the concentration of GHK-Cu is the same. 

Does this help blemish-prone skin? Just as a note – none of our products can be considered medical treatments for acne, so we suggest consulting with your physician to see what may work best for your skin.

Now that there is no more mixing involved with version 3, is the shelf life shorter than with CAIS 2? The shelf life is the same.

Looking forward to trying this out. Have you your similar product from the Ordinary. We hope you love it! You may wish to also explore The Ordinary “Buffet” + Copper Peptides 1%.

NIOD CAIS3 Reviews

Coming soon…

NIOD CAIS3 Ingredients

Aqua (Water), Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate, Tripeptide-1 Acetate, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.

Other Copper Products by Deciem

Where to buy NIOD

There are many places to buy NIOD. You can find a whole list of Deciem stores and online stockists here. Deciem offers free delivery on orders over 25€$. You can always find discounts on NIOD of sometimes up to 25%.